Workshop #1

Better late than never. 9.12.07

-*lecture lecture lecture* *angry voice*
-Drawing of glucose. Wikipedia - Glucose
-Best kinetic Stability
-Most efficient structure

-Drawing of ribose. Wikipedia - Ribose
dG > 0 => Expending Work / Non Spontaneous
dG < 0 =""> Gives off energy / Spontaneous

dG : Gibbs Free Energy

-No one likes peanuts.

Workshop # 2

In order for molecules to bond with each other, they must be at the correct speed and orientation.

This is where enzymes come in- they lower entropy and make it more likely moelcules will bond!

ATP hydrolysis has FREE ENERGY, so it is delta G NEGATIVE

To make a reaction go, you need activation energy.

polypeptide= amino acid chain...... amino acid chain=polypeptide

PHOSPHODIESTER BONDS connect nucleotides ( C3-O-P-O-C5 )

COUPLING is when you use a delta G negative reaction to fuel a delta G positive reaction

Think: Guy wants to lift weights, which has a positive delta G of 50. He eats a powerpar which contains a negative delta G of 60. Now he can lift the weights, and he releases the extra 10 as heat.

ATP is a high energy intermediate. During hydrolysis, a phosphate group is removed---this releases energy which can be used to bond nucleotides!

The End

Workshop #2

No Fun Fact
No Quote of the Day

Remember this:

BOLD WORDS = KEY WORDS

• Dr. Olek will make the calculations easy
• Ignore extra info like pH 7 @ 25 degrees C
  
• Spontaneous reactions => deltaG is negative at equilibrium
• a negative deltaG means free energy is released and can be used to do other work like COUPLING
  
• Activation Energy is needed to get to the transition state
• a Phosophodiester Bond links nucleotides ==> NOTE: THIS WILL BE ON THE TEST SO KNOW HOW TO DRAW THEM
• polymerization is the joining of nucleotides
  
• polypeptides are amino acid chains (proteins)
• Collision model = slow process because it depends on speed of molecules (energy) and orientation
  
• enymes lower entropy

Problem solving 101

1. list givens
2. draw diagram (may be a waste of time but if it helps do it)
3. find important relationships, proportions, whatever.
4. calculate
   

Thats it

Mooncai

P.S. For Ben and other freshmen. Clubs are for a meals, a side, and a fountain drink. Declining is money only for food and can be used everywhere. Flex or what they are now calling URos is money for everything.

Workshop #1

Fun Fact: Don't download music or else the school will find.

Quote of the day: "To do well in Bio 110 you have to give Olek what he wants" -Derek
......and what might that be ;)

so heres the notes-
*Ring shape is the most efficient
*AMP= adenine monophosphate
*ADP= adenine diphosphate
*ATP= adenine triphosphate

Radio labeling - used to find things later

filter - can be used to separate product from reactant when different sizes

****Important**** DONT include solids and pure liquids (H2O) in reactant for Keq

*6.02x10^23 is molecules per mole

In the Beginning.

Well well well, nice of you to join the party. And by party I mean Biology 110. This is the greatest class EVER, and if you don't agree, I will fight you.1 I'm Derek, your TA. I'll be helping you out this semester, and im really looking forward to working with each and every one of you.2 I hope the semester has started off nicely for you! Please, this blog is for you, so abuse it! Feel free to post any questions, comments or insights you may be having at the time of publication. Im looking forward to having a great semester with ya'll.3


1 I have never once fought someone, ever. (assume this to be a trend)
2 That was a very vague, blanket statement meant to make you feel good inside. By no means is it a personal insight, as I dont know a single one of you. I can assert, however, that by the time you are reading this I will have met you (or soon will) and will have a strong desire to get to know you and make your wildest biology dreams come true. (This is a sincerely genuine comment)
3 I reside in the state of New York, which is in the northeastern United States, where is is very rare, if not wrong, to use the phrase "ya'll". I may or may not continue using it. Because I'm a rebel. I also say "pop"-all the time.